Mathematical Modelling in Physiology: Biomedical Applications

Days 1,2,3: sessions at the room 727, INM RAS, Gubkin 8.
Coffee breaks and lunches, dinner (Day 1) at the room 630.
Banquet (Day 2) at the 9th floor.
Day 4: sessions at MIPT, Klimentovsky 1 bld.1

Day 1: Mathematical models in physiology I

8.30-9.00 Registration
Session I, chairman: Yuri Vassilevski
9.00-9.20 Introduction by workshop coordinators: Igor Efimov, Perumal Nithiarasu
9.20-10.00 Keynote lecture: Igor Efimov, Moscow Institute of Physics and Technology, The George Washington University. From animal models to human physiology
10.00-10.40 Keynote lecture: Yiannis Ventikos, University College London. Integrative modelling of brain transport phenomena: from hydrocephalus to dementia
10.40-11.00 Coffee break
Presentations of early career researchers
Session II, chairman: Igor Efimov
11.00-11.20 Igor Chernyavsky, University of Nottingham. Understanding flow and transport in the human placenta: a stochastic homogenization approach
11.20-11.40 Mainul Haque, University of Nottingham. Effect of positive end-expiratory pressure in patients with acute respiratory distress syndrome
11.40-12.00 Laura Nicolaou, Imperial College London. Flow and aerosol deposition in the respiratory airways
12.00-12.20 Alexey Kuchumov, Perm National Research Polytechnic University. Biomechanical models for normal and pathological bile flow in extra-hepatic biliary ducts
12.20-12.40 Marat Kamaltdinov, Perm National Research Polytechnic University. Simulation of the multiphase flow in the antroduodenum taking into account functional disorders
12.40-13.00 Aleksey Belyaev, Lomonosov Moscow State University. Computer simulations of blood platelet adhesion and aggregation under flow
13.00-13.20 Valeriya Maryakhina, Orenburg State University. The experimental and theoretical investigation of diffusion processes in biological liquid flow
13:20-14:20 Lunch
Presentations of early career researchers
Session III, chairman: Perumal Nithiarasu
14:20-14:40 Sergey Simakov, Moscow Institute of Physics and Technology. Mathematical modelling of blood flow in biomedical applications
14:40-15:00 Timur Gamilov, Moscow Institute of Physics and Technology. Modelling of 1D blood vessels under external pressure exemplified by fractional flow reserve computations
15:00-15:20 Tatiana Dobroserdova, Institute of Numerical Mathematics RAS, Moscow. Two problems of geometrical multiscale blood flow modelling
15:20-15:40 Akexander Khe, Lavrentyev Institute of Hydrodynamics, Novosibirsk. Haemodynamics of giant and multiple cerebral aneurysms
15:40-16:00 Alexander Cherevko, Lavrentyev Institute of Hydrodynamics, Novosibirsk. Using nonlinear oscillator as local hemodynamic model
16:00-16:20 Daniil Parshin, Lavrentyev Institute of Hydrodynamics, Novosibirsk. Advantages of Van der Pol-Duffing mathematical model of cerebrovascular hemodynamics
16:20-16:40 Raoul van Loon, Swansea University. “tbc”
16:40-17:00 Coffee break
17:00-18:40 Opportunities for early career researchers in the UK and in Russia
18:40-19:30 Dinner
20:00-21:00 Cultural event 1

Day 2: Mathematical models of the heart and the vascular system

Session IV, chairman: Gennady Bacharov
9.00-9.40 Keynote lecture: Perumal Nithiarasu, Swansea University. Importance of translational biomedical modelling research
9.40-10.20 Keynote lecture: Alexander Panfilov, MIPT, Ghent University. Anatomically accurate modelling of the electrical and mechanical function of the human heart
10.20-10.40 Coffee break
Presentations of early career researchers
Session V, chairman: Alexander Panfilov
10:40-11:00 Ankush Aggarwal, Swansea University. Determining functional properties of heart valves in-vivo using inverse modeling tools
11:00-11:20 Eugene TY Chang, The University of Sheffield. Uncertainty quantification in models of atrial fibrillation
11:20-11:40 Yulia Korneva, Smolensk State Medical University. Confirmation of death cases due to ventricular fibrillation using computational methods in practice of pathologists
11:40-12:00 Anastasia Khokhlova, Institute immunology and physiology RAS, Yekaterinburg. Influence of stretch on transmural gradient in mechanical function of isolated ventricular cardiomyocytes: experimental and modelling study
12:00-12:20 Sergey Pravdin, Institute of Mathematics and Mechanics RAS, Yekaterinburg. Study of scroll waves drift in a model of cardiac left ventricle
12:20-12:40 Fyodor Syomin, Lomonosov Moscow State University. Numerical simulation of changes in the heart performance with variation of haemodynamic parameters based on a cylindrical model of the left ventricle
12:40-13:00 Roman Syunyaev, Moscow Institute of Physics and Technology. The sinoatrial node model
13:00-13:20 Ekaterina Beklemysheva, Moscow Institute of Physics and Technology. Numerical modelling of low-velocity strike on human thorax: age-dependant response of the aorta.
13:20-14:20 Lunch
Session VI, chairman: Igor Sazonov
14:20-14:50 Keynote Lecture: Dimitris Parthimos, Swansea University. Ca2+ dynamics in arterial vasomotion
Presentations of early career researchers
14:50-15:10 Etienne Boileau, Swansea University. Human cardiac systems electrophysiology: from generic models to human stem-cell-derived cardiomyocyte
15:10-15:30 Amir Keshmiri, Manchester Metropolitan University. How can computational fluid dynamics help cardiovascular surgeons save more lives?
15:30-15:50 Zhuo Cheng, Imperial College London. Assessment of hemodynamic conditions in the aorta following root replacement with composite valve-conduit graft
15:50-16:10 Alberto Coccarelli, Cardiff University. Computing heat-transfer for a human body under hypothermia conditions
16:10-16:30 Katharine Fraser, University of Bath. Consideration of transient influences on red blood cell trauma in mechanical circulatory support
16:30-16:50 Coffee break
Professional networking session
Session VII, chairman: Yuri Vassilevski
16:50-17:20 Kulberg N. S, Sergunova K. A., Scientific practical center of medical radiology of Moscow, Usanov M. S., Dorodnicyn Computing Centre RAS,
New approach to processing and analysis of medical diagnostic visualization data in healthcare system of Moscow
17:20-17:50 Kirill Peskov, “M&S Decisions” LLC,
Model-based drug development: new trends and opportunities for the pharmaceutical industry
17:50-18:20 Discussion
19:00-22:00 Banquet

Day 3: Mathematical models in physiology II (!sessions may be shifted to afternoon if Cultural event 2 will be in the morning)

Session VIII, chairman: Dimitris Parthimos
9.00-9.40 Keynote lecture: Gennady Bocharov, Institute of Numerical Mathematics RAS. Mathematical modelling of immuno-physiological processes in virus infections
9.40-10.10 Keynote lecture: Igor Sazonov, Swansea university. Study of pulse reflection from a model aneurysm
10.10-10.30 Coffee break
Presentations of early career researchers
Session IX, chairman: Yiannis Ventikos
10:30-10:50 Tan Sui, University of Oxford. Hierarchical modelling and X-ray analysis of human dental tissues
10:50-11:10 Alexander Danilov, Institute of Numerical Mathematics RAS, Moscow. Image segmentation and skeletonization: application to hemodynamics modelling
11:10-11:30 Chang Sub Park, University of Oxford. A model of tissue movement during microwave ablation
11:30-11:50 Emilie Sauvage, University College London. Blood flow simulation and early steps towards FSI on patient-specific data
11:50-12:10 Dan Liu, University of Oxford. Kinetic study of 18F-FLT uptake in head and neck squamous cell carcinoma
12:10-12:30 Ann Smith, Cardiff University. Analysis of 16S rRNA gene data using Illumina MiSeq next generation sequencing
12:30-13:30 Lunch
13:30-18:00 Cultural event 2

Day 4: Discussions, Round Table

10:00-10:30 MIPT research in modeling for biomedical applications
10:30-11:00 Biomedical applications at the Institute of Mechanics, MSU
11:00-11:30 Biomedical modeling in hematology
11:30-12:00 Biomedical research at Sechenov First Moscow State Medical University
12:00-13:30 International Round Table “International cooperation: new perspectives on joint research projects”
13:30-13:40 Closing
13:40-14:40 Lunch
14:40-17:00 Cultural event 3